Table 4: Adverse effects and response status.

Adverse reactionGrade
I-IIIII-IVTotal

Local reaction000 (10)
Fever101 (10)
Rash000 (10)
Digestive discomfort 000 (10)
Arthralgia101 (10)
Anaphylactoid reaction000 (10)
Tumor lysis syndrom000 (10)
Laryngeal edema101 (10)
Fatigue303 (10)
Headache 000 (10)
Muscular soreness101 (10)