Combination with Methotrexate and Cyclophosphamide Attenuated Maturation of Dendritic Cells: Inducing Treg Skewing and Th17 Suppression In Vivo

Table 6

Comparison of DC surface antigen’s expression in each group on 9th week.

Groups	𝑛	BMDC surface antigen’s expression (𝑋±𝑆, %)
		CD11c	CD40	CD80	CD86	MHC-II
OVA	5	85.60±3.41	67.40±3.56	87.20±2.87	76.70±2.97	81.50±3.11
MTX	6	84.42±5.56	63.65±1.82^∗	83.62±2.14^∗	73.37±1.41^∗	78.17±2.02^∗
CTX	5	83.78±1.46	62.92±2.08^∗	82.70±1.66^∗	72.00±2.45^∗	75.32±2.09^∗
MTX and CTX	6	83.32±1.81	59.47±2.27^∗#△	79.17±1.94^∗#△	68.17±2.07^∗#△	71.87±2.20^∗#△

Values are expressed as mean ± standard deviation; the difference among groups was determined by ANOVA analysis and comparison between two groups was analyzed by the t-test. The DC surface antigen’s expression was significantly decreased in MTX combined with CTX group.
*Compared with 0 week, 𝑃<0.05; ^#compared with 3rd week, 𝑃<0.05; ^△compared with 6th week, 𝑃<0.05.