Combination with Methotrexate and Cyclophosphamide Attenuated Maturation of Dendritic Cells: Inducing Treg Skewing and Th17 Suppression In Vivo

Table 7

Stimulation index of mixed lymphocytes stimulated by BMDC on 9th week.

Groups	𝑛 (number of wells)	T-cells proliferation (cpm)
		𝑋±𝑆	𝐹	𝑃
T-cell Control	9	17169.86±2307.08^△▴
OVA	9	28734.21±1091.63^∗△▴
MTX	9	23318.43±528.13^∗#	38.45	<0.001
CTX	9	20484.83±2472.63^∗#
MTX and CTX	9	16043.62±1721.36^#△▴

Values are expressed as mean ± standard deviation; the difference among groups was determined by ANOVA analysis and comparison between two groups was analyzed by the t-test.
*Compared with T cell Control, 𝑃<0.05; ^#compared with OVA group, 𝑃<0.05; ^△compared with MTX group, 𝑃<0.05; ^▲compared with CTX group, 𝑃<0.05.