Table 1: Novel drugs for multiple myeloma bone disease.

Name of the drugActionBone target cell/s

DenosumabRANKL neutralizing antibodyOCs
LY2127399BAFF neutralizing antibodyOCs
MLN3897CCR1 inhibitorOCs
BHQ880DKK1 neutralizing antibodyOBs
ACE-011 (sotatercept)Activin A neutralizing receptor OCs and OBs