Review Article
Cellular Mechanisms of Multiple Myeloma Bone Disease
Table 1
Novel drugs for multiple myeloma bone disease.
| Name of the drug | Action | Bone target cell/s |
| Denosumab | RANKL neutralizing antibody | OCs | LY2127399 | BAFF neutralizing antibody | OCs | MLN3897 | CCR1 inhibitor | OCs | BHQ880 | DKK1 neutralizing antibody | OBs | ACE-011 (sotatercept) | Activin A neutralizing receptor | OCs and OBs |
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