Upregulated MicroRNA-155 Expression in Peripheral Blood Mononuclear Cells and Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
Figure 4
Altered expression of miR-155 by transfection of miR-155 inhibitor and mimic separately. (a) Transfection of miR-155 inhibitor (100 nM) for 48 h significantly decreased miR-155 level by at least 80% in RA-FLS. (b) Transfection of miR-155 mimic (100 nM) for 48 h induced at least 1000-fold increase in miR-155. miR-155 level was determined using qRT-PCR. Three independent experiments were carried out, and each experiment was done in three replicates.
