Immunomodulatory Effect of Bisphosphonate Risedronate Sodium on CD163+ Arginase 1+ M2 Macrophages: The Development of a Possible Supportive Therapy for Angiosarcoma
Figure 3
DTX with or without RS effects on the production of CXCL10, CXCL11, CCL17, CCL18, CCL22, and IL-10. The culture supernatants of M2 macrophages stimulated with DTX and/or RS were collected at 48 h after culture. Their chemokine and cytokine production was measured by ELISA. Representative data from at least three independent experiments are shown.