Assessment of T Regulatory Cells and Expanded Profiling of Autoantibodies May Offer Novel Biomarkers for the Clinical Management of Systemic Sclerosis and Undifferentiated Connective Tissue Disease

Table 2

Frequency of anti-nuclear antibodies and fluoroscopic patterns.

Anti-nuclear antibodies	Diagnosis			𝑃
(ANA)	lcSSc (14)	dcSSc (11)	UCTD (23)
P/N	14 (100%)	8 (73%)	20 (87%)
Titer; (range)	1 : 5120; (1 : 640–1 : 5120)	1 : 5120; (1 : 80–1 : 5120)	1 : 320; (1 : 80–1 : 1280)
Centromere	11 (78.6 % )	1 (12.5%)	0	<0.0001
Nucleolar	3 (21.4%)	0	5 (25.0%)	n.s.
Homogeneous and nucleolar	0	6 (75.0 % )	0	<0.0001
Speckled	0	0	15 (75.0 % )	<0.0001
Mitotic Spindle	0	1 (12.5%)	0	n.s.