B Epitope Multiplicity and B/T Epitope Orientation Influence Immunogenicity of Foot-and-Mouth Disease Peptide Vaccines

Figure 5

Frequency of peptide- and virus-specific IFNγ-producing cells in the spleen of immunized mice. IFNγ-producing cells were measured by ELISPOT assay in four animals from each group. Cells were stimulated with peptide (white bars) or FMDV (grey bars). Data are presented as the mean for four mice; error bars represent standard deviation.