Role of Toll-Like Receptor 4 on Lupus Lung Injury and Atherosclerosis in LPS-Challenge ApoE^−/− Mice

Table 1

Sera ANA (ug/mL) and anti-dsDNA (U/mL) levels in LPS-challenged mice.

	ApoE^−/− (𝑛=10)		Wild-type mice (𝑛=10)
	ANA	Anti-dsDNA	ANA	Anti-dsDNA
NS	93.4±7.9^$	(2.7±0.5)×10^4$	40.8±5.2	(2.4±0.6)×10^4
LPS	145.5±19.2^∗$	(8.0±1.3)×10^4∗$	58.5±8.2^∗	(4.1±0.4)×10^4∗
LPS + TAK-242	125.6±21.3^$	(4.2±0.8)×10^4#$	44.8±5.9	(2.9±0.9)×10^4#

^∗𝑃<0.05  versus  corresponding NS group, ^#𝑃<0.05  versus  corresponding LPS group, and ^$𝑃<0.05  versus  wild-type mice. ANA: anti-nuclear antibody (ANA); anti-dsDNA: anti-double-stranded deoxyribonucleic acid; NS: physiological saline; LPS: lipopolysaccharide; TAK-242: resatorvid.