Clinical Differences between Men and Women with Psoriatic Arthritis: Relevance of the Analysis of Genes and Polymorphisms in the Major Histocompatibility Complex Region and of the Age at Onset of Psoriasis

Table 1

Clinical characteristics of the study population.

Variables	Men	Women	𝑃 values
	n: 55	n:  55
Age (yr)	46.5±11.6	46.4±15.9	NS
Psoriasis onset age (yr)	27.5±10.4	27.0±14.9	NS
Arthritis onset age (yr)	34.2±9.4	35.1±13.1	NS
Psoriasis duration (yr)	19±11	18.2±8.8	NS
Arthritis duration (yr)	13±7.4	12.5±6.7	NS
Psoriasis-arthritis latency (yr)	7±6.4	7.5±5.6	NS
Family history	40%	45.5%	NS
Oligoarthritis	42%	34.5%	NS
Polyarthritis	20%	40%	<0.05
Axial disease	38.2%	23.6%	NS
Nail disease	36.4%	47.3%	NS
DIP disease	29%	34.5%	NS
IBP (ever)	62%	67.3%	NS
Enthesitis	34.5%	25.5%	NS
Dactylitis	31%	31%	NS
HAQ	0.62±0.42	1.10±0.53	<0.01
Swelling joint count	3.4±4.2	5.2±4.6	<0.05
Tender joint count	10.2±3.4	11.0±4.1	NS
Erosive disease	34.5%	41.8%	NS
PASI	5.4±4.5	5.7±3.8	NS
VSG	15±5.3	16±4.7	NS
HLA-C*06	56.4%	56.4%	NS
HLA-B27	36.4%	27.3%	NS

DIP: distal interphalangeal joint. IBP: inflammatory back pain. HAQ: Health Assessment Questionnaire. PASI: Psoriasis Area and Severity Index.