Journal of Immunology Research / 2013 / Article / Tab 1 / Review Article
Modification of Intestinal Microbiota and Its Consequences for Innate Immune Response in the Pathogenesis of Campylobacteriosis Table 1 Summary of altered bacteria ratios in named noninfectious diseases.
Noninfectious disease Names of bacteria altered References Type 1 diabetes Decrease in Lactobacillus spp. [43 ] Type 2 diabetes Increase in Bacillus spp. and Lactobacillus spp. [44 ] Obesity Increase in Bacteroidetes Decrease (to low numbers) in Bifidobacteria spp. [49 , 50 ] Inflammatory bowel disease (including Crohn’s disease and ulcerative colitis) Increase in Enterobacteriaceae Decrease in Bacteroidetes and certain Firmicutes [46 , 51 ] Irritable bowel syndrome Twofold increase in Firmicutes compared to Bacteroidetes with increase in Clostridia spp. and decrease in Bifidobacteria spp. [47 ] Celiac disease Increase in Lactobacillus spp., Bacteroides spp., Staphylococcus spp., and E. coli . In some cases levels of Bifidobacteria spp. increase, while there is reduction in some cases. In children, there is increase in Firmicutes and low levels of Bacteroidetes . [48 , 52 –54 ]