Heterozygous Alterations of TNFRSF13B/TACI in Tonsillar Hypertrophy and Sarcoidosis

Table 2

Allele frequency (%) of TNFRSF13B/TACI polymorphisms in the patients of the study.

Disease	No	Nonsynonymous SNPs		Synonymous SNPs			Intronic SNPs*
		V220A; rs56063729	P251L; rs34562254	27T; rs8072293	97P; rs35062843	277S; rs11078355	g.24625A>C; rs2274892	g.33402T>G; rs11652843	g.33482T>C; rs11652811
Sarcoidosis	71	3.52	16.90	71.83	3.52	43.66	48.49	29.58	29.58
TH group 1	19	0	15.79	73.68	2.63	50.00	39.47	26.32	26.32
TH group 2	15	3.33	20.0	80.00	3.33	46.67	50.00	20.00	20.00

SNPs: single nucleotide polymorphisms; TH group 1: tonsillar hypertrophy without infectious causative; TH group 2: tonsillar hypertrophy caused by H. influenzae.
∗The TNFRSF13B/TACI gene numbering is according to GenBank accession number AB22299.