Research Article

Persistent Suppression of Type 1 Diabetes by a Multicomponent Vaccine Containing a Cholera Toxin B Subunit-Autoantigen Fusion Protein and Complete Freund’s Adjuvant

Figure 7

Vaccinia virus-specific humoral immune response in NOD mice. ((a) Exp. no. 1 and (b) Exp. no. 2). Determination of the VV-specific IgG was performed using indirect ELISA in two separate experiments. Naive (PBS), CFA (1 : 10), and CFA (1 : 100) mice served as controls for absence of VV-specific antibodies, while rVV-L15-treated [10] mice were controls for autoantigen-expressing virus rVV-CTB::GAD.
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(a)
578786.fig.007b
(b)