Induction of Th17 Lymphocytes and Treg Cells by Monocyte-Derived Dendritic Cells in Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus
Figure 5
Induction of Treg lymphocytes by mo-DCs from patients with RA and SLE. Monocyte derived DCs generated under tolerizing conditions (PDL-1, PSGL-1 engagement, or IL-10 addition) or not, were cocultured with autologous CD4+ lymphocytes for five days. Then, the percent of CD4+ CD25+ Foxp3+ lymphocytes was determined by flow cytometry. Data correspond to the median and interquartile range of the percent of positive cells. *.
