Expression and Function of the Homeostatic Molecule Del-1 in Endothelial Cells and the Periodontal Tissue
Figure 3
Expression of Del-1 and endothelial cell adhesion molecules and bone loss as a function of age. (a) Gingiva dissected from WT mice at the indicated ages were processed for quantitative real-time PCR analysis of mRNA expression of the indicated genes; results were normalized to those of GAPDH mRNA and expressed as fold change in transcript levels relative to those of 5-week-old WT mice, the average value of which was taken as 1. (b) Time course of naturally occurring bone loss in aging WT mice in comparison to age-matched mice; negative values indicate bone loss relative to bone measurements in 5-week-old wild-type mice. Data are means ± SD ( mice per group). * as compared to 5-week-old WT mice (a) or between and WT mice (b).
