Modulation of LPS-Induced CD4+ T-Cell Activation and Apoptosis by Antioxidants in Untreated Asymptomatic HIV Infected Participants: An In Vitro Study

Table 2

The %CD25 expression before and after overnight stimulation with LPS and incubation with vitamin C and/or NAC.

% CD25	HIV+ group	Controls	𝑃 value between HIV and control	𝑃 value for LPS activation and inhibition by antioxidants in HIV group	𝑃 value for control
Unstimulated	7.9 (7.1–14.4)	10.2 (7.8–14.4)	0.4047
LPS stimulated	12.5 (10.3–17.6)	11.6 (9.6–15.2)	0.6823	0.0337**	0.16
LPS + Vit C	15.2 (11.7–17.6)	8.6 (7.2–11.9)	0.0003**	0.4	0.01**
LPS + NAC	9.0 (7.1–14.2)	9.9 (6.9–13.1)	0.9033	0.0416**	0.07
LPS + cocktail	6.0 (4.2–13.1)	9.1 (7.8–14.6)	0.0501	0.0018**	0.22

All the values are median (interquartile range) percentages of cells expressing CD25 of the HIV positive and control groups, unstimulated and stimulated with LPS and incubated overnight. **Medians significant at 𝑃<0.05.