Modulation of LPS-Induced CD4+ T-Cell Activation and Apoptosis by Antioxidants in Untreated Asymptomatic HIV Infected Participants: An In Vitro Study

Table 3

The % annexin V+/7-AAD− staining of the HIV positive and the control groups.

% Annexin V	HIV positive group	Control	𝑃 value (HIV and controls)	𝑃 value for LPS activation and inhibition by antioxidants in HIV+ group	𝑃-value for controls
Unstimulated	1.6 (0.9–4)	1.9 (1.2–2.3)	0.49
LPS-activated cells	3.3 (1.6–5.6)	2.5 (2.0–3.2)	0.17	0.11	0.007**
LPS + VIT C	3.6 (1.9–4.2)	2.6 (2.1–3.4)	0.26	0.84	0.44
LPS + NAC	3.4 (1.2–4.3)	2.6 (2.2–3.4)	0.55	0.54	0.66
LPS + CKTL	1.8 (1.0–3.7)	1.9 (1.5–2.4)	0.96	0.02**	0.008**

All the values are median (interquartile range) percentages of cells staining with annexin V/7-AAD− of the HIV positive and control groups, unstimulated and stimulated with LPS and incubated overnight. *Medians are marginally significant at 𝑃=0.05. **Medians significant at 𝑃<0.05.