Modulation of LPS-Induced CD4+ T-Cell Activation and Apoptosis by Antioxidants in Untreated Asymptomatic HIV Infected Participants: An In Vitro Study

Table 4

The % annexin V+/7-AAD+ staining of the HIV positive and HIV negative groups.

%7-AAD	HIV positive group	Control	𝑃 value between HIV and control	𝑃 value for LPS activation and inhibition by antioxidants in HIV group	𝑃 values for the controls
Baseline	0.7 (0.4–2.2)	0.4 (0.3–0.5)	0.02**
LPS-activated cells	1.9 (0.7–3.2)	0.6 (0.4–0.7)	0.0029**	0.10	0.14
LPS + VIT C	1.2 (0.7–2.7)	0.7 (0.4–1.0)	0.0048**	0.89	0.27
LPS + NAC	2.4 (1.0–3.4)	0.6 (0.4–0.8)	0.0003**	0.64	0.79
LPS + CKTL	1.8 (1.3–2.1)	0.7 (0.6–1.2)	0.0001***	0.76	0.56

The values are median (interquartile range) percentages of cells staining for both annexin V and 7-AAD of the HIV positive and control groups, unstimulated and stimulated with LPS and incubated overnight. **Medians significant at 𝑃<0.05. ***Medians significant at 𝑃≤0.0001.