Detection of Antiphosphatidylserine/Prothrombin Antibodies and Their Potential Diagnostic Value

Table 3

Association between the presence of antiphospholipid antibodies and LA activity.

Antibody		Lupus anticoagulant activity
		𝑃 value	Odds ratio (95% Cl)
aCL	IgG	<0.001	5.0 (2.4–10.6)
	IgM	<0.001	4.6 (1.6–13.7)
Anti-𝛽2GPI	IgG	<0.001	9.0 (4.2–19.4)
	IgM	<0.001	1.2 (1.0–1.4)
In-house aPS/PT	IgG	<0.001	21.6 (8.1–57.7)
	IgM	<0.001	12.9 (5.4–30.6)
QUANTA Lite aPS/PT	IgG	<0.001	15.3 (5.8–40.5)
	IgM	<0.001	13.2 (5.6–30.8)
	LAC	<0.001	10.2 (4.4–23.6)

aCL: anticardiolipin, anti-𝛽₂GPI: anti-𝛽₂glycoprotein, and aPS/PT: antiphosphatidylserine/prothrombin.