Protective Effects of HBSP on Ischemia Reperfusion and Cyclosporine A Induced Renal Injury

Figure 4

Apoptotic cells, labeled by fragmented DNAs, were mainly shown in tubular areas (a, d) and interstitial areas (b, c); some in tubular lumens (e); others with polymorphous nuclei ((f), yellow arrow). The number of apoptotic cells was significantly increased in the IR and IR + CsA kidneys but decreased by HBSP (g). Data are expressed as mean number per high power field of each group (mean ± SEM; 𝑛=6). ^∗𝑃<0.05; ^∗∗𝑃<0.01.

(a) Normal

(b) I only

(c) IR

(d) IR + CsA

(e) IR + CsA + HBSP

(f) IR + HBSP

(g)