Protective Effects of HBSP on Ischemia Reperfusion and Cyclosporine A Induced Renal Injury

Figure 6

The majority of active caspase-3+ cells, detected by immunostaining (a–f), were demonstrated morphologic features of apoptosis such as condensed nuclei. HBSP significantly decreased active caspase-3+ cells in both the IR kidneys and IR + CsA kidneys (g). Data are expressed as mean number per high power field of each group (mean ± SEM; 𝑛=6). ^∗𝑃<0.05; ^∗∗𝑃<0.01.

(a) Normal

(b) I only

(c) IR

(d) IR + CsA

(e) IR + CsA + HBSP

(f) IR + HBSP

(g)