P53 and Expression of Immunological Markers May Identify Early Stage Thyroid Tumors

Table 4

Comparison between p53 IHC profile and corresponding TP53 genotype.

	Altered cases		Wild-type cases		𝑃 value
	Mean	Median	Mean	Median
Intron 2	73.35	71.79	83.42	77.99	N.S.
Exon 4	66.68	77.10	76.20	83.42	N.S.
Exon 6	69.78	70.70	73.15	82.83	N.S.
Intron 7	72.70	81.39	76.55	90.72	N.S.
Intron 3	92.61	*	73.59	82.15	*
Intron 10	Tissue unavailable for IHC analysis		73.61	82.15	—
Exon 10	94.80	*	73.74	83.43	*
Intron 8	95.66	*	77.34	83.43	*

∗Analysis was not possible because only one patient had alterations.