Table 2: Age-dependent differences in cell autonomous immunity to L. monocytogenes.

EffectorRole in listeriosisNeonatal mouseNeonatal human

Recognition of L. monocytogenes (i) TLR/Myd88??
(ii) Cytosolic surveillance??
(iii) Inflammasome??
Intracellular fate of L. monocytogenes (i) Phagocytosis??
(ii) Autophagy??
(iii) IFN-inducible GTPases??
Fate of L. monocytogenes-infected monocyte(i) Apoptosis??
(ii) Necrosis??
(iii) Pyroptosis??