Age-Dependent Differences in Systemic and Cell-Autonomous Immunity to L. monocytogenes

Table 2

Age-dependent differences in cell autonomous immunity to L. monocytogenes.

Effector	Role in listeriosis	Neonatal mouse	Neonatal human
Recognition of L. monocytogenes	(i) TLR/Myd88	?	?
	(ii) Cytosolic surveillance	?	?
	(iii) Inflammasome	?	?
Intracellular fate of L. monocytogenes	(i) Phagocytosis	?	?
	(ii) Autophagy	?	?
	(iii) IFN-inducible GTPases	?	?
Fate of L. monocytogenes-infected monocyte	(i) Apoptosis	?	?
	(ii) Necrosis	?	?
	(iii) Pyroptosis	?	?