An Imbalance between Frequency of CD4+CD25+FOXP3+ Regulatory T Cells and CCR4+ and CCR9+ Circulating Helper T Cells Is Associated with Active Perennial Allergic Conjunctivitis
Figure 1
Frequency of CD25+ cells and CD4+CD25+FOXP3+ regulatory T cells in peripheral blood mononuclear cells. (a) Frequency of CD4+, CD25+, and double positive to CD4+CD25+ cells in PBMC from HC and PAC patient. (b) Same dot plot as (a); CD4+ cells gated as previously described in materials and methods, showing a gate performed to analyse CD4+CD25+ double positive cells. (c) Histogram from CD4+CD25+ gated cells (gated in (b)); the -axis denotes FOXP3 (MFI = mean fluorescence intensity). These dot plots and histograms are representative of 7 HC and 14 PAC patients.
