An Imbalance between Frequency of CD4+CD25+FOXP3+ Regulatory T Cells and CCR4+ and CCR9+ Circulating Helper T Cells Is Associated with Active Perennial Allergic Conjunctivitis

Table 3

Cytokines concentration in supernatants of cell culture.

	RPMI; MD (IQR-Range)	Der p; MD (IQR-Range)	Con A; MD (IQR-Range)	𝑃
				RPMI versus Der p	Der p versus Con A
IL-1𝛽	55.6; (50.2±63.6)	52.4; (44.3±67.9)	115; (96.9±205)	0.99	0.01
IL-6	118.9; (72.3–291.2)	480.6; (284±515.3)	2554; (1724±6239)	0.01	0.001
IL-8	13579; (11145±14853)	14753; (14332±18661)	12657; (11094±14287)	0.04	0.01
IL-10	62.51; (55.9–104.9)	69.1; (60.8–175.4)	243; (173–324)	0.32	0.09
IL-12p70	51.6; (50.5–63.9)	48.1; (46.4–49.2)	4458; (2077–6951)	0.06	0.001
TNF-𝛼	34.9; (33.0–61.8)	32.3; (31.23–34.7)	6942; (4070–19610)	0.07	0.0007

MD: Median; IQR: Interquartile range.
Results are in pg/mL; kit detection limits were as follows: IL-1𝛽: 3.7 pg/mL; IL-6: 4.7 pg/mL; IL-8: 3.4 pg/mL; IL-10: 4.1; IL-12p70: 4.0; TNF-𝛼: 3.9 pg/mL.