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Clinical and Developmental Immunology
Volume 2013 (2013), Article ID 932318, 11 pages
Research Article

A Full GMP Process to Select and Amplify Epitope-Specific T Lymphocytes for Adoptive Immunotherapy of Metastatic Melanoma

N. Labarriere,1,2,3 A. Fortun,1,2,3 A. Bellec,4 A. Khammari,1,2,3,5 B. Dreno,1,2,3,4,5 S. Saïagh,4 and F. Lang1,2,3

1Inserm, U892, 44000 Nantes, France
2Université de Nantes, 44000 Nantes, France
3CNRS, UMR 6299, 44000 Nantes, France
4Unit of Cell and Gene Therapy, CHU Nantes, 44000 Nantes, France
5Unit of Skin Cancer, CHU Nantes, 44000 Nantes, France

Received 18 July 2013; Revised 27 August 2013; Accepted 27 August 2013

Academic Editor: John Maher

Copyright © 2013 N. Labarriere et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • Inge Marie Svane, and Els M. Verdegaal, “Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve standard of care?,” Cancer Immunology, Immunotherapy, 2014. View at Publisher · View at Google Scholar
  • Ronald Rooke, “Can Calcium Signaling be harnessed for cancer immunotherapy?,” Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2014. View at Publisher · View at Google Scholar
  • Fernando Aranda, Erika Vacchelli, Florine Obrist, Alexander Eggermont, Jérôme Galon, Wolf Hervé Fridman, Isabelle Cremer, Eric Tartour, Laurence Zitvogel, Guido Kroemer, and Lorenzo Galluzzi, “Trial Watch: Adoptive cell transfer for anticancer immunotherapy,” OncoImmunology, vol. 3, no. 3, pp. e28344, 2014. View at Publisher · View at Google Scholar
  • Amir Khammari, Jean-Michel Nguyen, Melanie Saint-Jean, Anne-Chantal Knol, Marie-Christine Pandolfino, Gaelle Quereux, Anabelle Brocard, Lucie Peuvrel, Soraya Saiagh, Vincent Bataille, Jean-Marc Limacher, and Brigitte Dreno, “Adoptive T cell therapy combined with intralesional administrations of TG1042 (adenovirus expressing interferon-γ) in metastatic melanoma patients,” Cancer Immunology, Immunotherapy, 2015. View at Publisher · View at Google Scholar
  • X Wang, and I Rivière, “Manufacture of tumor- and virus-specific T lymphocytes for adoptive cell therapies,” Cancer Gene Therapy, 2015. View at Publisher · View at Google Scholar
  • N. Labarriere, Sylvain Simon, Virginie Vignard, Laetitia Florenceau, B. Dreno, A. Khammari, and F. Lang, “PD-1 expression conditions T cell avidity within an antigen-specific repertoire,” OncoImmunology, pp. 00–00, 2015. View at Publisher · View at Google Scholar