Rapamycin Ameliorates Proteinuria and Restores Nephrin and Podocin Expression in Experimental Membranous Nephropathy

Figure 7

Immunofluorescence staining for nephrin and podocin. HC: healthy controls; PHN: Passive Heymann Nephritis; PHN-Rapa: Passive Heymann Nephritis after rapamycin administration. Nuclei have been stained with propidium iodide (red). Intense (3+) linear staining in the HC and PHN-Rapa groups in contrast to the PHN group which presented attenuated and irregular pattern of staining for both nephrin and podocin (middle panel).