Table 3: Comparison in genotype and allele frequencies of −174G/C and −572G/C polymorphisms between the groups with rheumatoid arthritis and controls.

GenotypePolymorphism −174G/C Polymorphism −572G/C
RA
(%)
Controls
(%)
OR
(95% CI)
RA
(%)
Controls
(%)
OR
(95% CI)

GG106 (77.4)80 (78.4)0.940.84574 (54)62 (60.8)0.760.295
GC30 (21.9)20 (19.6)(0.48–1.82)58 (42.3)37 (36.3)(0.44–1.32)
CC1 (0.7)2 (2)5 (3.6)3 (2.9)
Allele
 G242 (88.3)180 (88.2)1.010.976206 (75.2)161 (78.9)0.810.338
 C32 (11.7)24(11.8)(0.57–1.8)68 (24.8)43 (21.1)(0.1–1.28)

RA: Rheumatoid arthritis; OR: odds ratio; 95% CI: confidence interval. For genotype, OR was computed using GG as a risk factor and GC + CC as the referent.