Research Article
Highlights on Novel Technologies for the Detection of Antibodies to Ro60, Ro52, and SS-B
Table 3
Overview of discrepant samples sorted according to disease state.
| Sample ID | Diagnosis | QUANTRIX (cut-off = 6 U/mL) | D-tek Dot Blot | QUANTA Flash Ro52 (cut-off = 20 CU) | BioPlex 2200 (Ro52) (cut-off = 1.0) |
| ASX~0039 | SjS | Not tested | 1 | 30.2 | 0.2 | ASX~0068 | SjS | 12 | 1 | 30.8 | 0.5 | BEx0026 | SjS | 12 | 1 | 25 | 0.7 | BEx0042 | SjS | 14 | 1 | 27.6 | 0.9 | BEx0040 | SLE | 7 | 1 | 24.3 | 0.2 | BEx0046 | UCTD | 10 | 1 | 56.4 | 0.4 | BEx0058 | UCTD | 0 | 0 | 21.4 | 0.2 | ASX~0088 | RA | 40 | 1 | 254.9 | 0.2 | BSX0053 | RA | Not tested | 1 | 200.2 | 0.2 | BSX0056 | RA | Not tested | 1 | 55.6 | 0.2 | BSX0035 | AT | Not tested | 0 | 69.2 | 0.2 |
| Sample ID | Diagnosis | QUANTRIX (cut-off = 6 U/mL) | D-tek Dot Blot | QUANTA Flash Ro60 (cut-off = 20 CU) | BioPlex 2200 (Ro60) (cut-off = 1.0) |
| BEx0006 | UCTD | Not tested | 0 | 4.9 | 8 | BEx0051 | UCTD | 0 | 0 | 4.9 | 1.2 | BEx0056 | UCTD | 0 | 0 | 8.2 | 1.1 |
| Sample ID | Diagnosis | QUANTRIX (cut-off = 6 U/mL) | D-tek Dot Blot | QUANTA Flash SSB (cut-off = 20 CU) | BioPlex 2200 (SSB) (cut-off = 1.0) |
| BEx0001 | SjS | 0 | 0 | 8.4 | 3 | BEx0014 | SjS | 0 | 0 | 24.8 | 0.9 | BEx0035 | SjS | 0 | 0 | 13.1 | 8 | BEx0036 | SjS | Not tested | Not tested | 25.5 | 0.2 | ASX~0076 | SLE | 0 | 0 | 16.6 | 8 | ASX~0082 | SLE | 0 | 0 | 8.5 | 8 | BEx0054 | SLE | 0 | 0 | 3.3 | 1 | BEx0013 | UCTD | Not tested | 0 | 4.2 | 8 | BEx0022 | UCTD | 0 | 0 | 3.3 | 1.2 | BEx0030 | UCTD | Not tested | 0 | 3.3 | 8 | BEx0033 | UCTD | Not tested | 1 | 225.8 | 0.2 | BEx0037 | UCTD | 0 | 0 | 5.3 | 1.9 | BEx0058 | UCTD | 0 | 0 | 5.5 | 1.2 | BEx0067 | UCTD | 0 | 0 | 5.1 | 4.7 | BEx0068 | UCTD | 0 | 0 | 3.3 | 1.8 | BEx0069 | UCTD | 0 | 0 | 3.3 | 2.7 | ASX~0098 | RA | 0 | 0 | 3.3 | 1.2 | BEx0060 | RA | 0 | 0 | 16 | 2.4 | BSX0043 | RA | 0 | 0 | 3.3 | 4.2 | BSX0091 | HI | 0 | 0 | 3.3 | 1.1 |
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AT: atopic dermatitis; HI: healthy individual; UCTD: undifferentiated connective tissue disease; RA: rheumatoid arthritis; SjS: Sjögren syndrome; SLE: systemic lupus erythematosus.
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