Clinical Study

Immunological Aspects in Late Phase of Living Donor Liver Transplant Patients: Usefulness of Monitoring Peripheral Blood CD4+ Adenosine Triphosphate Activity

Table 1

Characteristics of the 49 patients.

Age 51 (20–69)
Male/female33/16
Etiology of LDLT
 HCV (HCC)11 (6)
 HBV (HCC)11 (3)
 NBNC (HCC)10 (1)
 PBC6
 Others11

Median months after LDLT54.6 (12.2–111.5)

Laboratory data
 AST (U/L)41.4 (14–257)
 TB (mg/dL)1.5 (0.3–3.7)
 WBC (mm−3)6161 (2480–10480)

Dose of tacrolimus (mg/day)2.3 (0.5–8)
Blood concentration of tacrolimus (ng/mL)5.4 (0.4–10.3)
C/D ratio (ng/mL per mg/kg/day)170.3 (40.3–599.5)

LDLT: living donor liver transplantation, HCV: hepatitis C virus, HCC: hepatocellular carcinoma, HBV: hepatitis B virus, PBC: primary biliary cirrhosis, LC: liver cirrhosis, FH: fulminant hepatitis, ALT: alanine aminotransferase, TB: total bilirubin, WBC: white blood cell count, C/D ratio: tacrolimus concentration/dose ratio.