Research Article
Increased IL-33 in Synovial Fluid and Paired Serum Is Associated with Disease Activity and Autoantibodies in Rheumatoid Arthritis
Table 2
Correlation analysis between SF-serum IL-33 (pg/mL) and clinical and laboratory variables.
| Measurements | SF IL-33 () | Serum IL-33 () | r | P | r | P |
| Age (yrs) | −0.106 | 0.257 | −0.014 | 0.921 | Tender joint count, 0–46 joints | 0.095 | 0.347 | 0.327 | 0.020
*
| Swollen joint count, 0–48 joints | 0.192 | 0.056 | 0.134 | 0.354 | DAS28-ESR | 0.209 | 0.047
*
| 0.253 | 0.102 | ESR (mm/h) | 0.256 | 0.008
*
| 0.213 | 0.150 | CRP (mg/L) | 0.166 | 0.073 | 0.219 | 0.116 | C3 (g/L) | 0.113 | 0.260 | 0.267 | 0.061 | C4 (g/L) | 0.039 | 0.698 | 0.180 | 0.211 | IgA (g/L) | 0.246 | 0.012
*
| 0.107 | 0.457 | IgG (g/L) | 0.309 | 0.001
*
| 0.136 | 0.343 | IgM (g/L) | 0.301 | 0.002
*
| 0.220 | 0.121 | RF-IgM (U/mL) | 0.327 | <0.001
*
| 0.342 | 0.011
*
| RF-IgG (IU/mL) | 0.214 | 0.037
*
| 0.183 | 0.208 | GPI (mg/L) | 0.364 | 0.001
*
| 0.505 | 0.000
*
| Anti-CCP (RU/mL) | 0.104 | 0.284 | 0.052 | 0.716 |
|
|
P < 0.05. Spearman's correlation test was used.
|