Research Article

Glioma-Associated Antigen HEATR1 Induces Functional Cytotoxic T Lymphocytes in Patients with Glioma

Figure 1

HEATR1 was overexpressed in GBM and in A2B5+GSCs. (a) qRT-PCR was performed to analyze the differential expression between GBM tissues ( ) and controlled brain tissues ( ). (b)-(c) IHC was performed in FFPE tissue sections of 10 primary GBM tissues (left, ×400) and 10 normal brain tissues (right, ×400). GBM tissues had higher staining score of HEATR1 protein than normal brain tissues ( ). (d) qRT-PCR was performed to analyze the differential expression between A2B5+U87 cells and A2B5−U87 cells ( ).
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