Research Article
Glioma-Associated Antigen HEATR1 Induces Functional Cytotoxic T Lymphocytes in Patients with Glioma
Table 1
Clinical characteristics of healthy donors and patients.
| Number | Gender | Years | Tumor location | Pathology | Grade | ELISpot response | HLA-A2 |
| 198 | M | 54 | | Healthy | | Negative | Yes | 203 | M | 55 | | Healthy | | Negative | Yes | 205 | F | 56 | | Healthy | | Negative | Yes | 209 | F | 45 | | Healthy | | Negative | Yes | 219 | M | 22 | | Healthy | | Negative | No | 306 | M | 31 | | Healthy | | Negative | No |
| 215 | F | 48 | Right frontal | Meningioma | 0 | Negative | Yes | 216 | F | 62 | Cerebellum | Hemangioblastoma | 0 | Negative | No | 255 | F | 59 | Left frontal | Meningioma | 0 | Negative | Yes | 226 | F | 49 | Sellar region | Pituitary adenoma | 0 | Negative | Yes | 261 | M | 21 | Sellar region | Pituitary adenoma | 0 | Negative | No |
| 122 | M | 45 | Right temporal | Astrocytoma | 2 | Negative | No | 135 | F | 37 | Right temporal | Astrocytoma | 2 | Negative | Yes | 217 | M | 48 | Right frontal | Astrocytoma | 2 | Negative | No | 246 | F | 30 | Left parietal | Astrocytoma | 2 | Negative | Yes | 252 | M | 50 | Right temporal | Oligodendroglioma | 2 | Negative | No | 264 | M | 45 | Right frontal-callosum | Astrocytoma | 2 | Negative | Yes | 262 | M | 40 | Left temporal | Oligodendroglioma | 2 | Negative | Yes |
| 218 | M | 58 | Right temporal | AA | 3 | Negative | Yes | 238 | F | 56 | Right callosal convolution | AO | 3 | Negative | No | 254 | F | 33 | Right frontal | AOA | 3 | Negative | Yes | 256 | F | 46 | Right temporal-basal ganglia | AA | 3 | Negative | No | 259 | F | 58 | Right parietal | AO | 3 | Negative | No | 265 | M | 56 | Right frontal-parietal | AOA | 3 | Negative | No | 127 | F | 42 | Left frontal | AA | 3 | Positive | No | 140 | M | 45 | Left temporal | AA | 3 | Positive | A0201/A1101 | 156 | M | 48 | Left occipital | AE | 3 | Positive | A0203/A3001 | 239 | M | 16 | Left temporal | AA | 3 | Positive | A0207/A1102 |
| 129 | F | 38 | Left occipital | GBM | 4 | Negative | Yes | 133 | F | 48 | Left temporal | GBM | 4 | Negative | No | 147 | F | 61 | Left temporal | GBM | 4 | Negative | Yes | 150 | M | 48 | Right frontal-temporal | GBM | 4 | Negative | Yes | 151 | M | 30 | Right temporal | GBM | 4 | Negative | Yes | 214 | M | 66 | Right parietal-occipital | GBM | 4 | Negative | No | 223 | M | 37 | Left frontal-temporal | GBM | 4 | Negative | Yes | 224 | M | 59 | Left temporal-occipital | GBM | 4 | Negative | Yes | 225 | M | 31 | Left frontal | GBM | 4 | Negative | No | 231 | M | 36 | Left frontal | GBM | 4 | Negative | No | 241 | M | 58 | Right frontal | GBM | 4 | Negative | Yes | 253 | M | 54 | Left frontal | GBM | 4 | Negative | No | 132 | M | 68 | Right temporal | GBM | 4 | Positive | A0201/A0203 | 141 | F | 12 | Right parietal-occipital | GBM | 4 | Positive | No | 220 | M | 47 | Left temporal | GBM | 4 | Positive | A0201/A3303 | 221 | F | 39 | Right temporal | GBM | 4 | Positive | No |
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: recurrence; F: female; M: male; GBM: glioblastoma multiforme; AA: anaplastic astrocytoma; AO: anaplastic oligodendroglioma; AOA: anaplastic oligoastrocytoma; AE: anaplastic ependymoma.
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