Clinical Study
High Prevalence of Antinuclear Antibodies in Children with Thyroid Autoimmunity
Table 2
Associated autoimmune diseases in ANA-positive and ANA-negative children with AITD and in their parents.
| | Patients | ANA positive () | ANA negative () | |
| Associated autoimmune diseases (/%)
| 14/66 (21%) | 6/27 (22%) | 0.87 | | Celiac disease () | 6 | 3 | | | Type 1 DM () | 2 | 2 | | | Autoimmune gastritis () | 2 | 0 | | | Vitiligo () | 2 | 0 | | | Alopecia () | 1 | 1 | | | Autoimmune thrombocytopenia () | 1 | 0 | |
| | Parents | 66 mothers, 66 fathers | 27 mothers, 27 fathers | |
| | Autoimmune diseases in parents (/%) | 27/132 (20.4%) | 16/54 (29.6%) |
0.24 |
| | Autoimmune diseases in mothers () | 18 | 10 | | | AITD () | 14 | 10 | | | SLE () | 1 | 0 | | | Sjogren’s syndrome () | 1 | 0 | | | Autoimmune thrombocytopenia (N) | 1 | 0 | | | Autoimmune diseases in fathers () | 9 | 6 | | | AITD () | 8 | 4 | | | Vitiligo () | 1 | 1 | | | Rheumatoid arthritis () | 0 | 1 | |
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Type 1 DM: type 1 diabetes mellitus; AITD: autoimmune thyroid disease; SLE: systemic lupus erythematosus.
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