Long-Lasting Production of New T and B Cells and T-Cell Repertoire Diversity in Patients with Primary Immunodeficiency Who Had Undergone Stem Cell Transplantation: A Single-Centre Experience

Figure 1

((a) and (b)) Average frequency of children with SCID and PID receiving HSCT (HSCT-SCID and HSCT-PID, resp.) with values of KRECs and TRECs over the respective cut-offs, calculated in age-matched healthy children. ((c) and (d)) Average frequency of children with SCID and PID that were not subjects to HSCT (no-HSCT), with values of KRECs and TRECs over the cut-offs. The indicated time-classes for HSCT children were calculated starting from the date of HSCT, whereas in no-HSCT children each time-class represents the age at the time of sampling. Time-classes were indicated as follows: 1: <1 year, 2: <2 years, 3: <3 years, 4: <4 years, 5: <5 years, <10: <10 years, and >10: >10 years. Bars represent the means and error bars represent the standard deviations.