Research Article
Long-Lasting Production of New T and B Cells and T-Cell Repertoire Diversity in Patients with Primary Immunodeficiency Who Had Undergone Stem Cell Transplantation: A Single-Centre Experience
Table 1
Characteristics of the patients included in the study and of the transplants.
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ADA: adenosine deaminase; Artemis: DNA cross-link repair 1C gene; ATG: rabbit thymoglobulin; CD40 L: CD40 ligand; CHH: cartilage hair hypoplasia; CID: combined immunodeficiency; FHL: familial hemophagocytic lymphohistiocytosis; FOXN1: forkhead box N1 transcription factor; FOXP3: forkhead box P3; GvHD: graft-versus-host disease; HSCT: hematopoietic stem cell transplantation; IL2RG: interleukin 2 receptor, gamma gene; IL7R: interleukin 7 receptor; IPEX: immune dysregulation, polyendocrinopathy, and enteropathy; ITGB2: integrin beta 2; JAK3: Janus kinase 3; LAD-1: leukocyte adhesion deficiency type 1; mAbs: monoclonal antibodies; MMRD: mismatched related family donor; MSD: HLA-matched sibling donor; MUD: unrelated donor; PID: primary immunodeficiency; PRF: perforin 1 (pore forming protein); RAG: recombination activating genes; RMRP: RNA component of mitochondrial RNA processing endoribonuclease; PNP: purine nucleoside phosphorylase; SCID: severe combined immunodeficiency; TINF2: TRF1-interacting nuclear factor 2; XLA: X-linked agammaglobulinemia; XLT: X-linked thrombocytopenia. *Mean (months). |