Fusion-Expressed CTB Improves Both Systemic and Mucosal T-Cell Responses Elicited by an Intranasal DNA Priming/Intramuscular Recombinant Vaccinia Boosting Regimen
Figure 2
Specific antibody and T-cell immune responses elicited in respiratory tract. (a) Ovalbumin specific T-cell response in cervical and axillary lymph nodes. Significant differences were observed between rTTV-OVA-CTB boosting groups and rTTV-OVA boosting groups. (b) Specific IgA titer in bronchial alveolar lavage. The average OVA specific IgA titer induced by pSV-OVA priming/rTTV-OVA boosting was significantly higher than pSV-OVA priming/rTTV-OVA-CTB boosting group. , .
