Fusion-Expressed CTB Improves Both Systemic and Mucosal T-Cell Responses Elicited by an Intranasal DNA Priming/Intramuscular Recombinant Vaccinia Boosting Regimen
Figure 3
Specific antibody and T-cell immune responses elicited in female genital tract. (a) T lymphocytes responses in inguinal and iliac lymph nodes. The T-cell responses of rTTV-OVA-CTB boosting groups were significantly higher than those of rTTV-OVA boosting groups. (b) Specific IgG responses in vaginal lavage. No significant difference was found among different groups. (c) Specific IgA responses in vaginal lavage. IgA titer elicited by pSV-OVA-CTB priming/rTTV-OVA-CTB boosting group was significantly higher than pSV-OVA priming/rTTV-OVA-CTB boosting group. , .
