Journal of Immunology Research / 2014 / Article / Tab 1 / Research Article
The Robust and Modulated Biomarker Network Elicited by the Plasmodium vivax Infection Is Mainly Mediated by the IL-6/IL-10 Axis and Is Associated with the Parasite Load Characteristics Healthy donors HD Malaria patients MAL Gender, male/female 11/26 53/24 Median age, years (range) 27 (19–45) 35 (18–73) Number of malaria episodes,
(%) 1st — 15 (19.5) <5 — 35 (45.4) ≥5 — 27 (35.1) Parasitemia (parasites/mm3 ),
(%) Low, ≤500 — 39 (50.6) High, >500 — 38 (49.4) Symptoms,
(%) Fever — 53 (68.8) Myalgia — 64 (83.1) Headache — 71 (92.2) Chills — 58 (75.3) Sweating — 42 (54.5) Weakness — 67 (87.0) Hematological records Hemoglobin levels g/dL, median (range) 13.1 (11.4–16.2) 13.3 (8.4–17.1) Hematocrit %, median (range) 38.2 (32.1–46.9) 39.2 (24.0–49.9) Red blood cells ×106 /mm3 , median (range) 4.1 (3.4–5.7) 4.1 (2.6–5.3) White blood cells ×103 /mm3 , median (range) 5.9 (3.6–11.6) 4.4 (1.4–9.0) Platelets ×103 /mm3 , median (range) 242.0 (136.0–442.0) 119.0 (20.0–270.0)