Research Article
The Mosaic of “Seronegative” Antiphospholipid Syndrome
Table 1
Clinical characteristics of patients studied.
| | Characteristics (%) | SN-APS () | APS () |
| | Other autoimmune diseases | 17 (70.8) | 16 (64) | | SLE | 9 (37.5) | 16 (64) | | Sjögren syndrome secondary to SLE | 2 (8.3) | 8 (32) | | Primary Sjögren syndrome | 1 (4.2) | 0 | | Rhupus | 1 (4.2) | 0 | | Mixed connective tissue disease | 1 (4.2) | 0 | | Undifferentiated connective tissue | 1 (4.2) | 0 | | Disease | 1 (4.2) | 0 | | Urticarial vasculitis | 1 (4.2) | 0 | | LED | 1 (4.2) | 0 | | Myasthenia gravis | 0 | 1 (4) | | None | 5 (20.8) | 9 (36) | | Vascular thrombosis | 18 (75) | 24 (96) | | Venous thrombosis | 10 (41.6) | 17 (68) | | Arterial thrombosis | 12 (50) | 10 (40) | | Recurrent thrombosis | 8 (33.3) | 10 (40) | | Pregnancy morbidity | 8 (33.3) | 9 (36) | | Normal fetus deaths | 7 (29.2) | 2 (8) | | Premature births | 0 | 0 | | Spontaneous abortions | 5 (20.8) | 8 (32) | | Vascular thrombosis and pregnancy morbidity | 3 (12.5) | 6 (24) | | Noncriteria APS features | | | | Livedo reticularis | 5 (20.8) | 7 (28) | | Thrombocytopenia | 1 (4.2) | 5 (20) | | Cognitive dysfunctions | 1 (4.2) | 6 (24) | | Migraine | 5 (20.8) | 8 (32) | | Seizures | 0 | 5 (20) | | Brain MRI scan abnormalities | 10 (41.6) | 8 (32) | | Thrombotic risk factors | 15 (62.5) | 14 (56) | | Hypercholesterolemia | 5 (20.8) | 10 (40) | | Smoking | 12 (50) | 5 (20) | | Hypertension | 6 (25) | 7 (28) | | OC/HRT | 2 (8.3) | 2 (8) | | Diabetes mellitus | 1 (4.2) | 0 |
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