A Mycobacterium bovis BCG-Naked DNA Prime-Boost Vaccination Strategy Induced CD4⁺ and CD8⁺ T-Cell Response against Mycobacterium tuberculosis Immunogens

Table 1

Heterologous prime-boost immunization schedule.

Group	Prime	Boost1	Boost2
PBST	PBST	PBST	PBST
BCG-C	BCG-China	PBST	PBST
BCG-P	BCG-Pasteur1173	PBST	PBST
BCG-C+pcDNA3.1	BCG-China	Plasmid pcDNA3.1	Plasmid pcDNA3.1
BCG-P+pcDNA3.1	BCG-Pasteur1173	Plasmid pcDNA3.1	Plasmid pcDNA3.1
BCG-C+3.1-69	BCG-China	Plasmid pc-Rv1769	Plasmid Pc-Rv1769
BCG-P+3.1-69	BCG-Pasteur1173	Plasmid pc-Rv1769	Plasmid Pc-Rv1769
BCG-C+3.1-72	BCG-China	Plasmid pc-Rv1772	Plasmid Pc-Rv1772
BCG-P+3.1-72	BCG-Pasteur1173	Plasmid pc-Rv1772	Plasmid Pc-Rv1772
Timeline in weeks	0; ↓	3; ↓	6; ↓