Analysis of Autoantibodies to 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Using Different Technologies

Figure 4

Putative indirect immunofluorescence pattern on HEp-2 cells. A serum sample from a patient with anti-HMGCR antibodies was used to stain HEp-2 cells. On these cells, the fluorescence pattern suggestive for anti-HMGCR is a finely granular cytoplasmic staining on a minority (3% or less) of HEp-2000 cells with perinuclear reinforcement.