Transplant Glomerulopathy: The Interaction of HLA Antibodies and Endothelium
Figure 1
Histopathology of transplant glomerulopathy. (a) Light microscopy showing TG with a glomeruli showing sclerosis (periodic-acid-Schiff stain ×400). (b) Light microscopy showing glomerulitis (presence of mononuclear cells in glomerular capillaries) in a biopsy specimen (periodic-acid-Schiff stain ×600) (c) Silver staining highlighting double contouring of the glomerular capillary wall (×400). (d) Electron microscopy showing duplication of the glomerular basement membrane—arrows (×8000) (e) Peritubular capillitis (arrow) in a TG biopsy specimen (periodic-acid-Schiff ×600) (f) Peritubular C4d staining in a TG biopsy (immunofluorescence ×400).