Hepatitis E rORF2p Stimulated and Unstimulated Peripheral Expression Profiling in Patients with Self-Limiting Hepatitis E Infection

Figure 2

HEV rORF2p stimulated peripheral expression profiles in hepatitis E patients by flow cytometry. HEV rORF2p stimulated expression of inhibitory (CTLA-4, PD1L, and GITR), integrin (CD103), activation (CD25, CD69), and Treg-associated cytokines (IL10, TGF-β ₁) on PBMCs of AVH-E (a–h) and recovered (i); n = numbers of patients. Each dot represents an individual data point and the horizontal lines represent the mean. The ANOVA with Bonferroni post hoc corrections was used to compare differences among groups. Data are representative of mean ± SD.

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