HLA-G Expression on Blasts and Tolerogenic Cells in Patients Affected by Acute Myeloid Leukemia

Figure 3

Flow cytometric analysis of CD4⁺ T cells in the peripheral blood of AML patients. (a) Percentages of CD4⁺ T cells among the CD45^bright cells in the peripheral blood of AML patients (AML pts) and healthy donors (HDs) are shown. Each dot represents single AML patient or HD. Lines indicate the median and interquartile range of positive cells detected in all patients and donors analyzed. (b) Representative dot plots of HLA-G⁺ CD4⁺ T cells are depicted. (c) Percentages of HLA-G⁺ CD4⁺ T cells in patients with HLA-G⁺ or HLA-G⁻ blasts are shown. Each dot represents single AML patient. Lines indicate the median and interquartile range of HLA-G⁺ CD4⁺ T cells. **𝑃<0.01.

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