A Circulating Subpopulation of Monocytic Myeloid-Derived Suppressor Cells as an Independent Prognostic/Predictive Factor in Untreated Non-Small Lung Cancer Patients

<div>Kaplan-Meier plots of OS and PFS in patients according to the percentages of monocytic subpopulation (CD14<sup>+</sup>CD15<sup>+</sup>CD11b<sup>+</sup>CD33<sup>+</sup>HLA-DR<sup>−</sup>Lin<sup>−</sup>) of MDSCs before any systemic treatment. Comparison of (a) progression-free survival (PFS) and (b) overall survival (OS) between normal (<svg height="9.26535pt" id="M93" style="vertical-align:-1.16493pt" version="1.1" viewbox="-0.0498162 -8.10042 8.08224 9.26535" width="8.08224pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0135,0,0,-0.0135,0,0)"><path d="M531 71V127L115 310L531 494V550L57 335V285L531 71ZM531 -40V10H57V-40H531Z" id="g117-93"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g></svg>2.2%) and increased (<svg height="8.21822pt" id="M94" style="vertical-align:-0.6617599pt" version="1.1" viewbox="-0.0498162 -7.55646 8.08224 8.21822" width="8.08224pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0135,0,0,-0.0135,0,0)"><path d="M512 230V281L75 514V456L453 256V254L75 55V-3L512 230Z" id="g117-92"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g></svg>2.2%) percentages of CD14<sup>+</sup>CD15<sup>+</sup>CD11b<sup>+</sup>CD33<sup>+</sup>HLA-DR<sup>−</sup>Lin<sup>−</sup>MDSC.</div>

Journal of Immunology Research

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Figure 5

Figure 5: A Circulating Subpopulation of Monocytic Myeloid-Derived Suppressor Cells as an Independent Prognostic/Predictive Factor in Untreated Non-Small Lung Cancer Patients 

Figure 5 | A Circulating Subpopulation of Monocytic Myeloid-Derived Suppressor Cells as an Independent Prognostic/Predictive Factor in Untreated Non-Small Lung Cancer Patients 