A Circulating Subpopulation of Monocytic Myeloid-Derived Suppressor Cells as an Independent Prognostic/Predictive Factor in Untreated Non-Small Lung Cancer Patients

Table 3

T cells, B cells, DC/monocytes in the blood of NSCLC patients and healthy controls. Percentages of the cells in the peripheral blood of NSCLC patients and healthy controls as obtained by flow cytometry analysis. Percentages indicated in the plots represent the percentages of phenotypic marker expression in the parental population, which are presented in brackets. Data presented as Mean ± SEM of the. ( < 0.05, 0.001, 0.0001, resp.).

Cells	Healthy donors ( = 19)	NSCLC patients ( = 110)
	% cells ± SEM	% cells ± SEM
CD3^+CD4^+ (in lymphocytes)	58.7 ± 4.5	36.4 ± 2.1^****
CD3^+CD8^+ (in lymphocytes)	20.1 ± 2	20.6 ± 1.2
CD19^+ (in lymphocytes)	7.40 ± 0.9	8.20 ± 0.8
CD11b^+CD14^+ (lymphocytes excluded)	34.4 ± 4.6	18.8 ± 1.7^***
CD14^+HLA-DR^+Lin^− (CD14^+ cells)	63.1 ± 5.2	47.6 ± 2.6^*