Control of Intracellular Francisella tularensis by Different Cell Types and the Role of Nitric Oxide

Figure 2

((a) and (b)) Nitrite production from stimulated cells: J774A.1 (a) and MH-S (b). Stimulant concentrations added were IFN-𝛾 (1 μg/mL), LPS (5 μg/mL), and IFN-𝛾 + LPS (1 μg/mL + 5 μg/mL). Nitrite measurements were taken 24 hours after stimulation and/or infection. Values are the means and SEM from at least three independent experiments. Significant differences in production of nitrite from stimulation or stimulation and infection are marked with asterisks. Significance levels of *𝑃<0.05, **𝑃<0.01, and ***𝑃<0.001 by Student’s 𝑡-test.

(a)

(b)