Research Article

Isolated IgA Anti-β2 Glycoprotein I Antibodies in Patients with Clinical Criteria for Antiphospholipid Syndrome

Table 3

Positive aPL antibodies in C-APS patients versus controls.

Controls ( ) APS ( ) OR

aB2GPI IgG2 (0.6%)14 (8.9%)14.9<0.0001
aB2GPI IgM3 (0.9%)8 (5.1%)5.40.0146
aB2GPI IgA5 (1.6%)45 (28.8%)24.4<0.0001
aCL IgG3 (0.9%)17 (10.8%)12.3<0.0001
aCL IgM2 (0.6%)8 (5.1%)8.20.0053
aCL IgA3 (0.9%)8 (5.1%)5.50.0148
aB2GP1 IgA (isolated)5 (1.6%)35 (22.4%)17.4<0.0001
aCL or aB2GPI (IgG or IgM)6 (2.0%)22 (14.1%)8.2<0.0001
aCL or aB2GPI any isotype13 (4.2%)61 (39.1%)14.5<0.0001