Reestablishment of Active Immunity against HBV Graft Reinfection after Liver Transplantation for HBV-Related End Stage Liver Disease

Table 2

Data of the 50 cases at the time active immunity against HBV was reestablished.

Vaccine (Engerix-B/Twinrix)	20/30
Baseline anti-HBs titers (IU/L)	87.71 ± 38.82 (83.61, 23.90–195.30)
Number of cycles for reestablishment of immunity (, %)	First cycle: 22, 44%
	Second cycle: 22, 44%
	Third cycle: 6, 12%
Number of doses for reestablishment of immunity	5.06 ± 2.39 (5.00, 1.00–11.00)
Anti-HBs titer at reestablishment of immunity (IU/L)	264.91 ± 197.66 (198.64, 43.45–1000.0)
The highest anti-HBs titer (IU/L)	488.07 ± 322.52 (388.15, 95.81–1000.0)
The lowest anti-HBs titer^# (IU/L)	111.82 ± 74.53 (93.34, 25.53–410.40)
Number of booster vaccinations^#	1.61 ± 0.79 (1.00, 1–4)
The highest titer of sera anti-HBs after booster vaccination (IU/L)	438.09 ± 296.96 (313.70, 75.84–1000.00)

The upper limit of sera anti-HBs quantitative detection by ELISA (Roche) is 1000 IU/L.
^#The anti-HBs titer of 39 recipients had dropped to <100 IU/L or declined by 50% during the follow-up period, so the booster vaccinations were performed.